@article{kumar_ram_2019, 
  title={Analytical method development and validation of Amlodipine besylate in tablet dosage form}, 
  DOI={10.22270/jddt.v9i4-a.3459}, 
  abstractNote={<jats:p>The  accurate and precise HPLC analytical method validated for the determination of Amlodipine besylate  in pharmaceutical dosage form.The chromatographic separation is carried out on shimadzu HPLC system (LC-2010 CHT)  with  UV Vissible  detector and C18(150mm x3.9 mm) 5 μm Column. The Mobile phase consists of Acetonitrile: Methanol: PH 3.0 Buffer (15 V: 35 V: 50 V) , at the flow rate  of  1.0 ml/min and elutes were monitoring  at 237 nm. The observed retention time for Amlodipine besylate was 10.8 min. The % RSD for system precision was 0.41 % and Method precision was 0.58 %.  The method was found to linear (R=0.99996) in the Concentration range of 35-105 μg/ml (50 to 150%). The accuracy was in between 99.50-99.91%.&#x0D;
Keywords:  HPLC, Correlation coefficient, System suitability, Bias, % RSD and ICH guidelines</jats:p>}, 
  number={4-A}, 
  publisher={Society of Pharmaceutical Tecnocrats}, 
  author={Kumar, Sunil and Ram, Bigan}, 
  year={2019}, 
  month={Aug}
  }