Correlation Of Positive IgM or IgG RDT (Rapid Diagnostic Test) Results with CRP (C-Reactive Protein) Levels in Dengue Hemorrhagic Fever Patients release_crmkmrkf4bb3pfdtd5esy7d5gu

by Yaumi Tasu'a Salsabila, Pancawati Ariami, Ida Bagus Rai Wiadnya, Thomas Tandi Manu

Published in Jurnal Analis Medika Biosains (JAMBS) by Poltekkes Kemenkes Mataram.

2023   Volume 10, Issue 2, p93

Abstract

Background: Laboratory diagnosis of Dengue Hemorrhagic Fever includes the IgM & IgG RDT (Rapid Diagnostic Test) examination which differentiates primary and secondary dengue infection. The presence of inflammation in the body caused by the dengue virus needs to be examined for C-Reactive Protein. Methods: This research is an analytical observational study with a cross sectional approach. Thesample used is a plasma sample of a patient diagnosed with DHF with a positive IgM or IgG RDT result. Results: Positive IgM RDT results were 6 people (17%) and positive IgG were 30 people (83%). The results of a qualitative CRP study were 24 people (67%) with positive CRP levels. Semi-quantitative CRP average level for positive IgG was29.33. The results of the Spearman's Rank statistical test obtained a value of p = 0.003 <0.05 which showed a significant result. Conclusion:Clinically it shows that the more positive IgM or IgG RDT results obtained, the higher the CRP level which indicates the severity/inflammation that is formed in the body.
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