Liquid Chromatography-Mass Spectrometry: A Review
release_bmzza44l3jav7m7est57iqihfu
by
Rama Rao Tadikonda,
Thangadipalli Yashwanth,
Banuri Usha
2024 Volume 14, Issue 6, p298-304
Abstract
The analytical technique known as liquid chromatography-mass spectrometry is incredibly precise and sensitive. It's a really powerful tool. Detection, identification, and mass determination of components in the presence of additional components are carried out by mass spectrometry using sample eluents from liquid chromatography and mass spectrometry. Liquid chromatography is used to identify pharmaceutical medication components, intermediates, and related compounds for both quantitative and qualitative applications. Liquid chromatography is mostly used in-vitro dissolution, bioequivalence, bioavailability, and metabolite research. Liquid chromatography mass spectrometry is also used in forensic labs, agrochemical firms, fundamental research, and the food industry. Applications, instrumentation, and the liquid chromatography-mass spectrometry principle are covered in this review.
Keywords: Liquid Chromatography, Mass Spectrometry, High Performance Liquid Chromatography, Bioequivalence, Metabolite research.
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Date 2024-06-15
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2250-1177
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