Serum Albumin release_akalwiuk2zhwddl3qlmvm3cxtm

by Daria A. Belinskaia, Polina A. Voronina, Anastasia A. Batalova, Nikolay V. Goncharov

Published in Encyclopedia by MDPI AG.

2020   p65-75

Abstract

Being one of the most abundant proteins in human and other mammals, albumin plays a crucial role in transporting various endogenous and exogenous molecules and maintaining of colloid osmotic pressure of the blood. It is not only the passive but also the active participant of the pharmacokinetic and toxicokinetic processes possessing a number of enzymatic activities. A free thiol group of the albumin molecule determines the participation of the protein in redox reactions. Its activity is not limited to interaction with other molecules entering the blood: of great physiological importance is its interaction with the cells of blood, blood vessels and also outside the vascular bed. This topic review contains data on the enzymatic, inflammatory and antioxidant properties of serum albumin.
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Date   2020-12-27
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