Influenza C Virus CM2 Protein Is Produced from a 374-Amino-Acid Protein (P42) by Signal Peptidase Cleavage release_6b2aecixwzdznfubunjlixyqxa

by Seiji Hongo, Kanetsu Sugawara, Yasushi Muraki, Yoko Matsuzaki, Emi Takashita, Fumio Kitame, Kiyoto Nakamura

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FIG. 5. Proposed model for the biosynthesis of CM2. The 374-amino-acid protein (P42) has two hydrophobic domains capable of interacting with a lipid bi- layer (shaded) and a N-glycosylation site (CHO). This protein is cleaved by signal peptidase after Ala residue 259 to produce the M1Ј and CM2 proteins composed of the N-terminal 259 amino acids and C-terminal 115 amino acids, respectively.