Quinoline Alkaloids. Synthesis of Khaplofoline, Ribalinine, and Flindersine release_64jpmlhrtrdx3frla5tx7yhvvu

by M. Subramanian, P. S. Mohan, P. Shanmugam, K. J. Rajendra Prasad

Published in Zeitschrift für Naturforschung. B, A journal of chemical sciences by Walter de Gruyter GmbH.

1992   Volume 47, p1016-1020

Abstract

Reaction of 4-hydroxy-3-prenylquinolin-2(1 H)one (5 a) with iodine and silver acetate gave a iodopyranoquinoline (6 a), which was then converted into the alkaloids khaplofoline (1) and ribalinine (2). Reaction of 5a with iodine and mercuric oxide afforded a mixture of 6a and its angular isomer 7 a; the coversion of latter into flindersine (10) is described.
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Date   1992-07-01
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