Unleashing the potential: super-resolution microscopy as the key to advanced mitochondrial research
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Xiaoyu Li,
Miao He,
Xiaoshuai Huang
Abstract
<jats:title>Abstract</jats:title>
Investigating the fine structure of mitochondria and their dynamic interactions with other organelles is crucial for unraveling the mechanisms underlying mitochondrial-related diseases. The development of super-resolution techniques has provided powerful visualization tools for mitochondrial research, which is significant for investigating mitochondrial cristae structure, the localization of mitochondrial-related protein complex, and the interactions between mitochondria and other organelles. In this perspective, we introduce several advanced super-resolution techniques and their applications in mitochondrial research, and discuss the potential roles these techniques may play in future studies of mitochondria.
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