@article{krishnarajan_gowthaman_rao_chandra_pavan_sainudheen, 
  title={Effect of cellulose and non-cellulose polymers on ciprofloxacin extended release tablets}, 
  volume={2012}, 
  abstractNote={Sustained release delivery systems have shown to be of better significance in release rate for drugs [1]. The present study was an attempt to develop extended release tablets of Ciprofloxain HCl which on oral administration prolongs its release thereby increasing bioavailability, diminishing side effects and enhanced patient compliance. Ciprofloxacin HCl is used to treat a number of infections including: infections of bones and joints, endocardiasis, gasteroenteritis, prostatitis, anthrax and chancroid 5. Ciprofloxacin extended release tablets were formulated using polymers HPMC (K4M, K15M, K100M) and Carbopol 71G by wet granulation technique [2]. The prepared formulations were evaluated with pre-compression parameters like bulk density, compressibility index, hausner ratio, angle of repose and post-compression parameters like weight variation, thickness, hardness, friability, in-vitro dissolution study. The in-vitro dissolution study of formulation CE10 shows drug release within 24 hours.}, 
  author={Krishnarajan and Gowthaman and Rao and Chandra and Pavan and Sainudheen}
  }