abstracts[] |
{'sha1': '91ac3478752ad8c991b254e336e295c7de8e4c48', 'content': "Objective: This study aims to systematically and quantitatively analyze the impact of intensive clinical management of cardiovascular risk factors in patients with Type 1 Diabetes Mellitus (T1DM), focusing on the prevention of micro and macrovascular complications.\n\xa0\nTheoretical Framework: T1DM is an autoimmune disease associated with a high risk of vascular complications that significantly affect patients' quality of life and clinical outcomes. Intensive management strategies, including strict glycemic control, lifestyle modifications, and comorbidity treatment, have demonstrated efficacy in reducing adverse events. However, gaps remain regarding the durability of these benefits and the need for personalized approaches for different patient profiles.\n\xa0\nMethod: A systematic review was conducted using the PubMed, Scopus, and Web of Science databases, including studies published between 2015 and 2024. The inclusion criteria encompassed research evaluating the reduction of vascular complications, functional outcomes, efficacy of intensive management, and safety. The exclusion criteria eliminated studies without interventions related to cardiovascular risk factors or those without relevant outcome measures.\n\xa0\nResults and Discussion: The findings indicate that intensive clinical management significantly reduces the incidence of micro and macrovascular complications, such as nephropathy, retinopathy, and cardiovascular events, particularly when combined with behavioral changes. However, treatment response varies according to factors such as age, disease duration, and genetic profile. Multidisciplinary strategies and personalized interventions emerge as the most effective approaches to optimize outcomes and minimize risks.\nResearch Implications: This study reinforces the importance of long-term and multicenter clinical trials to establish standardized protocols and assess the efficacy and safety of intensive management. Future research should explore cost-effectiveness and the impact on patients' quality of life.\n\xa0\nOriginality/Value: This systematic review provides valuable evidence on the efficacy of intensive clinical management in controlling cardiovascular risk factors in patients with T1DM, contributing to more informed clinical decisions and better patient outcomes. The results highlight the relevance of individualized strategies in treating patients with T1DM and a high risk of vascular complications.", 'mimetype': 'application/xml+jats', 'lang': None}
|
container |
{'state': 'active', 'ident': '24p6hkl6wjfrlmo6kqdhgtdqi4', 'revision': '618a0d3c-8296-450f-832d-19ecb9a121fc', 'redirect': None, 'extra': {'country': 'br', 'languages': ['pt'], 'publisher_type': 'longtail', 'road': {'as_of': '2018-01-24'}, 'szczepanski': {'as_of': '2018'}, 'urls': ['https://rgsa.emnuvens.com.br/rgsa/index'], 'webarchive_urls': ['https://web.archive.org/web/20120713053654/http://www.revistargsa.org/ojs/index.php/rgsa/index']}, 'edit_extra': None, 'name': 'Revista de Gestão Social e Ambiental', 'container_type': None, 'publication_status': None, 'publisher': 'RGSA- Revista de Gestao Social e Ambiental', 'issnl': '1981-982X', 'issne': '1981-982X', 'issnp': None, 'wikidata_qid': 'Q50668312'}
|
container_id |
24p6hkl6wjfrlmo6kqdhgtdqi4
|
contribs[] |
{'index': 0, 'creator_id': None, 'creator': None, 'raw_name': 'Armando Lira Barros', 'given_name': 'Armando Lira', 'surname': 'Barros', 'role': 'author', 'raw_affiliation': None, 'extra': {'seq': 'first'}}
{'index': 1, 'creator_id': None, 'creator': None, 'raw_name': 'Ana Kallynne de Araújo Silva', 'given_name': 'Ana Kallynne de Araújo', 'surname': 'Silva', 'role': 'author', 'raw_affiliation': None, 'extra': None}
{'index': 2, 'creator_id': None, 'creator': None, 'raw_name': 'Raiana Santos Chaves Rangel', 'given_name': 'Raiana Santos Chaves', 'surname': 'Rangel', 'role': 'author', 'raw_affiliation': None, 'extra': None}
{'index': 3, 'creator_id': None, 'creator': None, 'raw_name': 'Ariele Renata Rodrigues Nascimento', 'given_name': 'Ariele Renata Rodrigues', 'surname': 'Nascimento', 'role': 'author', 'raw_affiliation': None, 'extra': None}
{'index': 4, 'creator_id': None, 'creator': None, 'raw_name': 'Caroline de Oliveira Gomes', 'given_name': 'Caroline de Oliveira', 'surname': 'Gomes', 'role': 'author', 'raw_affiliation': None, 'extra': None}
{'index': 5, 'creator_id': None, 'creator': None, 'raw_name': 'Yasmin Bandeira Ramos', 'given_name': 'Yasmin Bandeira', 'surname': 'Ramos', 'role': 'author', 'raw_affiliation': None, 'extra': None}
{'index': 6, 'creator_id': None, 'creator': None, 'raw_name': 'Maria Fernanda Haas Tonial', 'given_name': 'Maria Fernanda Haas', 'surname': 'Tonial', 'role': 'author', 'raw_affiliation': None, 'extra': None}
{'index': 7, 'creator_id': None, 'creator': None, 'raw_name': 'Lucas Paulo Bezerra', 'given_name': 'Lucas Paulo', 'surname': 'Bezerra', 'role': 'author', 'raw_affiliation': None, 'extra': None}
{'index': 8, 'creator_id': None, 'creator': None, 'raw_name': 'Maria Fernanda Seixas Oliveira', 'given_name': 'Maria Fernanda Seixas', 'surname': 'Oliveira', 'role': 'author', 'raw_affiliation': None, 'extra': None}
{'index': 9, 'creator_id': None, 'creator': None, 'raw_name': 'Rebecca Maria Gomes Oliveira', 'given_name': 'Rebecca Maria Gomes', 'surname': 'Oliveira', 'role': 'author', 'raw_affiliation': None, 'extra': None}
{'index': 10, 'creator_id': None, 'creator': None, 'raw_name': 'Maria Gabriella Simas Aranha Teixeira de Carvalho', 'given_name': 'Maria Gabriella Simas Aranha Teixeira de', 'surname': 'Carvalho', 'role': 'author', 'raw_affiliation': None, 'extra': None}
{'index': 11, 'creator_id': None, 'creator': None, 'raw_name': 'Luiza Carmita Assunção Mafra', 'given_name': 'Luiza Carmita Assunção', 'surname': 'Mafra', 'role': 'author', 'raw_affiliation': None, 'extra': None}
{'index': 12, 'creator_id': None, 'creator': None, 'raw_name': 'Ana Carolina Gadelha Sarmento', 'given_name': 'Ana Carolina Gadelha', 'surname': 'Sarmento', 'role': 'author', 'raw_affiliation': None, 'extra': None}
{'index': 13, 'creator_id': None, 'creator': None, 'raw_name': 'José Vinícius Avelino de Medeiros', 'given_name': 'José Vinícius Avelino de', 'surname': 'Medeiros', 'role': 'author', 'raw_affiliation': None, 'extra': None}
{'index': 14, 'creator_id': None, 'creator': None, 'raw_name': 'Marina de Queiroz Passos', 'given_name': 'Marina de Queiroz', 'surname': 'Passos', 'role': 'author', 'raw_affiliation': None, 'extra': None}
{'index': 15, 'creator_id': None, 'creator': None, 'raw_name': 'Júlia Emerenciano de Albuquerque Melo Trigueiro', 'given_name': 'Júlia Emerenciano de Albuquerque Melo', 'surname': 'Trigueiro', 'role': 'author', 'raw_affiliation': None, 'extra': None}
{'index': 16, 'creator_id': None, 'creator': None, 'raw_name': 'Fernanda Luiza Soares Ramos', 'given_name': 'Fernanda Luiza Soares', 'surname': 'Ramos', 'role': 'author', 'raw_affiliation': None, 'extra': None}
{'index': 17, 'creator_id': None, 'creator': None, 'raw_name': 'Luiz Eduardo Staufackar Carlos Costa', 'given_name': 'Luiz Eduardo Staufackar Carlos', 'surname': 'Costa', 'role': 'author', 'raw_affiliation': None, 'extra': None}
{'index': 18, 'creator_id': None, 'creator': None, 'raw_name': 'Brenda Chaves Alves', 'given_name': 'Brenda Chaves', 'surname': 'Alves', 'role': 'author', 'raw_affiliation': None, 'extra': None}
{'index': 19, 'creator_id': None, 'creator': None, 'raw_name': 'André Jereissati Melo Rodrigues', 'given_name': 'André Jereissati Melo', 'surname': 'Rodrigues', 'role': 'author', 'raw_affiliation': None, 'extra': None}
{'index': 20, 'creator_id': None, 'creator': None, 'raw_name': 'Filipe da Nóbrega Tomaz Moreira', 'given_name': 'Filipe da Nóbrega Tomaz', 'surname': 'Moreira', 'role': 'author', 'raw_affiliation': None, 'extra': None}
{'index': 21, 'creator_id': None, 'creator': None, 'raw_name': 'Artur Freire Brito', 'given_name': 'Artur Freire', 'surname': 'Brito', 'role': 'author', 'raw_affiliation': None, 'extra': None}
{'index': 22, 'creator_id': None, 'creator': None, 'raw_name': 'Luciano Victor Vasconcelos Saldanha', 'given_name': 'Luciano Victor Vasconcelos', 'surname': 'Saldanha', 'role': 'author', 'raw_affiliation': None, 'extra': None}
{'index': 23, 'creator_id': None, 'creator': None, 'raw_name': 'Caio Gabriel Rocha Ramos', 'given_name': 'Caio Gabriel Rocha', 'surname': 'Ramos', 'role': 'author', 'raw_affiliation': None, 'extra': None}
{'index': 24, 'creator_id': None, 'creator': None, 'raw_name': 'José Lucas Silva de Souza', 'given_name': 'José Lucas Silva de', 'surname': 'Souza', 'role': 'author', 'raw_affiliation': None, 'extra': None}
{'index': 25, 'creator_id': None, 'creator': None, 'raw_name': 'Paulo Mateus Barreto de Souza', 'given_name': 'Paulo Mateus Barreto de', 'surname': 'Souza', 'role': 'author', 'raw_affiliation': None, 'extra': None}
{'index': 26, 'creator_id': None, 'creator': None, 'raw_name': 'Maurício Aparecido Terrani Sentinella', 'given_name': 'Maurício Aparecido Terrani', 'surname': 'Sentinella', 'role': 'author', 'raw_affiliation': None, 'extra': None}
|
ext_ids |
{'doi': '10.24857/rgsa.v19n2-103', 'wikidata_qid': None, 'isbn13': None, 'pmid': None, 'pmcid': None, 'core': None, 'arxiv': None, 'jstor': None, 'ark': None, 'mag': None, 'doaj': None, 'dblp': None, 'oai': None, 'hdl': None}
|
files[] |
{'state': 'active', 'ident': 'tugs4bvzabaltiotmerzeoy7j4', 'revision': 'ba40541f-a541-41b3-b4ea-22ad29f33cb4', 'redirect': None, 'extra': None, 'edit_extra': None, 'size': 289459, 'md5': '9133fdcf2c4a737af3c513080389958a', 'sha1': 'fc0e11540bff2f761cf4f9b689acfb690fb81bcd', 'sha256': '6cafd23ed084ed4673c93cbb49b32c08b27e6b75f667d1a8bb380beb97c0c3c3', 'urls': [{'url': 'https://rgsa.openaccesspublications.org/rgsa/article/download/11269/6080', 'rel': 'publisher'}, {'url': 'https://web.archive.org/web/20250227060333/https://rgsa.openaccesspublications.org/rgsa/article/download/11269/6080', 'rel': 'webarchive'}], 'mimetype': 'application/pdf', 'content_scope': None, 'release_ids': ['3edycdug6beu5hjf77gqrp7c4u'], 'releases': None}
|
filesets |
[]
|
issue |
2
|
language |
|
license_slug |
CC-BY
|
number |
|
original_title |
|
pages |
e011269
|
publisher |
RGSA- Revista de Gestao Social e Ambiental
|
refs[] |
{'index': 0, 'target_release_id': None, 'extra': {'unstructured': 'ALEXANDER, Jason T. et al. The longer-term benefits and harms of glucagon-like peptide-1 receptor agonists: a systematic review and meta-analysis. Journal of general internal medicine, p. 1-24, 2022.'}, 'key': '262710', 'year': None, 'container_name': None, 'title': None, 'locator': None}
{'index': 1, 'target_release_id': None, 'extra': {'doi': '10.3390/jcm10081798', 'unstructured': 'COLOM, Cristina et al. Cardiovascular disease in type 1 diabetes mellitus: epidemiology and management of cardiovascular risk. Journal of clinical medicine, v. 10, n. 8, p. 1798, 2021.'}, 'key': '262711', 'year': None, 'container_name': None, 'title': None, 'locator': None}
{'index': 2, 'target_release_id': None, 'extra': {'doi': '10.1210/clinem/dgac485', 'unstructured': 'DONG, Yue et al. The risks of cardiovascular disease following weight change in adults with diabetes: a cohort study and meta-analysis. The Journal of Clinical Endocrinology & Metabolism, v. 107, n. 10, p. e4177-e4186, 2022.'}, 'key': '262712', 'year': None, 'container_name': None, 'title': None, 'locator': None}
{'index': 3, 'target_release_id': None, 'extra': {'doi': '10.3390/healthcare11081123', 'unstructured': 'FARHAT, Grace. Culturally tailored dietary interventions for improving glycaemic control and preventing complications in south asians with type 2 diabetes: Success and future implications. In: Healthcare. MDPI, 2023. p. 1123.'}, 'key': '262713', 'year': None, 'container_name': None, 'title': None, 'locator': None}
{'index': 4, 'target_release_id': None, 'extra': {'doi': '10.1117/12.3000022', 'unstructured': 'HAN, Siyuan. A review of type 1 diabetes. In: International Conference on Modern Medicine and Global Health (ICMMGH 2023). SPIE, 2023. p. 722-726.'}, 'key': '262714', 'year': None, 'container_name': None, 'title': None, 'locator': None}
{'index': 5, 'target_release_id': None, 'extra': {'doi': '10.1016/s2213-8587(17)30095-5', 'unstructured': 'HERRINGTON, William G.; PREISS, David. Tightening our understanding of intensive glycaemic control. The Lancet Diabetes & Endocrinology, v. 5, n. 6, p. 405-407, 2017.'}, 'key': '262715', 'year': None, 'container_name': None, 'title': None, 'locator': None}
{'index': 6, 'target_release_id': None, 'extra': {'doi': '10.1111/dme.13807', 'unstructured': 'HOLT, R. I. G. Lest we forget the microvascular complications of diabetes. Diabetic Medicine, v. 35, n. 10, 2018.'}, 'key': '262716', 'year': None, 'container_name': None, 'title': None, 'locator': None}
{'index': 7, 'target_release_id': None, 'extra': {'doi': '10.1080/13696998.2021.1963572', 'unstructured': 'JULIAN, Guilherme Silva et al. Cost of microvascular complications in people with diabetes from a public healthcare perspective: a retrospective database study in Brazil. Journal of Medical Economics, v. 24, n. 1, p. 1002-1010, 2021.'}, 'key': '262717', 'year': None, 'container_name': None, 'title': None, 'locator': None}
{'index': 8, 'target_release_id': None, 'extra': {'doi': '10.34172/hpp.2020.18', 'unstructured': 'MOBASSERI, Majid et al. Prevalence and incidence of type 1 diabetes in the world: a systematic review and meta-analysis. Health promotion perspectives, v. 10, n. 2, p. 98, 2020.'}, 'key': '262718', 'year': None, 'container_name': None, 'title': None, 'locator': None}
{'index': 9, 'target_release_id': None, 'extra': {'doi': '10.1097/mop.0000000000000915', 'unstructured': 'NIECHCIAŁ, Elżbieta; MARCOVECCHIO, M. Loredana. Treatment of cardiometabolic risk factors in patients with type 1 diabetes. Current Opinion in Pediatrics, v. 32, n. 4, p. 589-594, 2020.'}, 'key': '262719', 'year': None, 'container_name': None, 'title': None, 'locator': None}
{'index': 10, 'target_release_id': None, 'extra': {'doi': '10.7326/m15-1399', 'unstructured': 'PILLAY, Jennifer et al. Behavioral programs for type 1 diabetes mellitus: a systematic review and meta-analysis. Annals of Internal Medicine, v. 163, n. 11, p. 836-847, 2015.'}, 'key': '262720', 'year': None, 'container_name': None, 'title': None, 'locator': None}
{'index': 11, 'target_release_id': None, 'extra': {'doi': '10.1016/j.metabol.2020.154308', 'unstructured': 'PRATTICHIZZO, Francesco et al. Legacy effect of intensive glucose control on major adverse cardiovascular outcome: systematic review and meta-analyses of trials according to different scenarios. Metabolism, v. 110, p. 154308, 2020.'}, 'key': '262721', 'year': None, 'container_name': None, 'title': None, 'locator': None}
{'index': 12, 'target_release_id': None, 'extra': {'doi': '10.1007/s12020-022-03159-9', 'unstructured': 'RODRIGUEZ-GUTIERREZ, Rene et al. Intensive vs. conventional blood pressure goals in older patients with type 2 diabetes: a systematic review and meta-analysis. Endocrine, v. 78, n. 1, p. 13-23, 2022.'}, 'key': '262722', 'year': None, 'container_name': None, 'title': None, 'locator': None}
{'index': 13, 'target_release_id': None, 'extra': {'unstructured': 'SGP. Brasil ocupa terceira posição no ranking mundial de diabetes tipo 1 em crianças. Sociedade goiana de pediatria, 2024.'}, 'key': '262723', 'year': None, 'container_name': None, 'title': None, 'locator': None}
{'index': 14, 'target_release_id': None, 'extra': {'unstructured': 'SBEM. Números do Diabetes no Mundo. Sociedade brasileira de endocrinologia e metabologia, 2019.'}, 'key': '262724', 'year': None, 'container_name': None, 'title': None, 'locator': None}
{'index': 15, 'target_release_id': None, 'extra': {'doi': '10.34172/ijbsm.2023.07', 'unstructured': 'SEDIGHI, Mehrnoosh et al. A Comprehensive Review on Diabetes Mellitus and Its Relation to Other Diseases. International Journal of Basic Sciences in Medicine, v. 8, n. 1, p. 42-54, 2023.'}, 'key': '262725', 'year': None, 'container_name': None, 'title': None, 'locator': None}
{'index': 16, 'target_release_id': None, 'extra': {'doi': '10.3238/arztebl.2016.0816', 'unstructured': 'SCHORR, Susanne Gabriele et al. The prevention and treatment of retinal complications in diabetes. Deutsches Ärzteblatt International, v. 113, n. 48, p. 816, 2016.'}, 'key': '262726', 'year': None, 'container_name': None, 'title': None, 'locator': None}
{'index': 17, 'target_release_id': None, 'extra': {'doi': '10.1161/circulationaha.122.059430', 'unstructured': 'TABÁK, Adam G. et al. Risk of macrovascular and microvascular disease in diabetes diagnosed using oral glucose tolerance test with and without confirmation by hemoglobin A1c: the Whitehall II cohort study. Circulation, v. 146, n. 13, p. 995-1005, 2022.'}, 'key': '262727', 'year': None, 'container_name': None, 'title': None, 'locator': None}
{'index': 18, 'target_release_id': None, 'extra': {'doi': '10.1007/s00125-021-05491-7', 'unstructured': 'TREMBLAY, Johanne et al. Polygenic risk scores predict diabetes complications and their response to intensive blood pressure and glucose control. Diabetologia, v. 64, p. 2012-2025, 2021.'}, 'key': '262728', 'year': None, 'container_name': None, 'title': None, 'locator': None}
{'index': 19, 'target_release_id': None, 'extra': {'unstructured': 'TREMBLAY, J. et al. Polygenic risk scores predict diabetic complications and their response to therapy. MedRxiv, p. 19010785, 2019.'}, 'key': '262729', 'year': None, 'container_name': None, 'title': None, 'locator': None}
{'index': 20, 'target_release_id': None, 'extra': {'doi': '10.4274/jcrpe.galenos.2023.2023-12-12', 'unstructured': 'VURALLI, Doğuş et al. Cardiovascular risk factors in adolescents with type 1 diabetes: Prevalence and gender differences. Journal of Clinical Research in Pediatric Endocrinology, v. 16, n. 1, p. 11, 2024.'}, 'key': '262730', 'year': None, 'container_name': None, 'title': None, 'locator': None}
{'index': 21, 'target_release_id': None, 'extra': {'doi': '10.1210/clinem/dgac034', 'unstructured': 'YAPANIS, Michael et al. Complications of diabetes and metrics of glycemic management derived from continuous glucose monitoring. The Journal of Clinical Endocrinology & Metabolism, v. 107, n. 6, p. e2221-e2236, 2022.'}, 'key': '262731', 'year': None, 'container_name': None, 'title': None, 'locator': None}
{'index': 22, 'target_release_id': None, 'extra': {'doi': '10.1016/j.clinthera.2018.03.015', 'unstructured': 'ZHANG, Xinyue et al. Legacy effect of intensive blood glucose control on cardiovascular outcomes in patients with type 2 diabetes and very high risk or secondary prevention of cardiovascular disease: a meta-analysis of randomized controlled trials. Clinical Therapeutics, v. 40, n. 5, p. 776-788. e3, 2018.'}, 'key': '262732', 'year': None, 'container_name': None, 'title': None, 'locator': None}
|
release_date |
2025-02-26
|
release_stage |
published
|
release_type |
article-journal
|
release_year |
2025
|
subtitle |
|
title |
Analysis of the Impact of Intensive Clinical Management of Cardiovascular Risk Factors in Patients With Type 1 Diabetes: Prevention of Micro and Macrovascular Complications
|
version |
|
volume |
19
|
webcaptures |
[]
|
withdrawn_date |
|
withdrawn_status |
|
withdrawn_year |
|
work_id |
xtjmtxhg3rawfggnpswn2mwc2m
|